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Protagonist Therapeutics, Inc.

PTGX

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$ 103.87

-2.76 (-3.26%)

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Revenue	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Total Revenues	46.0	46.0	434.4	60.0	26.6	27.4	28.6	0.2	30.9	20.1	0.0	0.0	0.0
Cost of Revenues	0.4	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Gross Profit	45.6	44.8	434.4	60.0	26.6	27.4	28.6	0.2	30.9	20.1	0.0	0.0	0.0

Revenue	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Total Revenues	7.4	4.7	5.5	28.3	170.6	4.7	4.2	255.0	60.0	0.0
Cost of Revenues	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.8
Gross Profit	7.1	4.7	5.5	28.3	170.6	4.7	4.2	255.0	59.2	-0.8

Operating Income	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
R&D Expenses	0.0	0.0	0.0	120.2	126.2	126.0	74.5	65.0	59.5	46.2	25.7	11.8	7.5
Selling General & Admin Expenses	0.0	0.0	0.0	33.5	31.7	27.2	18.6	15.7	13.7	11.8	7.0	3.0	1.9
Depreciation & Amortization	1.3	1.2	0.8	3.3	3.4	0.3	0.9	2.8	0.5	0.4	0.3	0.2	0.3
Total Operating Expenses	203.8	202.9	181.6	153.7	158.0	153.2	93.1	80.8	73.2	58.0	32.7	14.8	9.3
Operating Income	-158.1	-158.1	252.8	-93.7	-131.4	-125.8	-64.5	-80.5	-42.3	-37.9	-32.7	-14.8	-9.3

Operating Income	TTM	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
R&D Expenses	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	28.9	30.7
Selling General & Admin Expenses	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.1	7.7
Depreciation & Amortization	0.4	0.4	0.3	0.2	0.5	0.6	1.5	0.2	0.8	0.8
Total Operating Expenses	57.4	51.1	47.6	47.6	43.9	46.1	43.0	48.6	37.0	38.3
Operating Income	-50.4	-46.4	-42.0	-19.3	126.8	-41.5	-38.8	206.3	23.0	-38.3

Net Income	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Interest Income	28.8	28.8	26.3	14.9	4.1	0.4	0.9	2.8	2.5	0.9	0.2	0.0	0.0
Interest Expense	0.0	0.0	0.0	0.0	-3.4	0.0	0.6	0.2	0.0	0.0	0.0	0.0	0.0
Other Expense	28.8	28.8	26.6	14.7	4.0	0.3	-0.3	2.6	2.5	0.9	-4.8	-0.1	-1.8
IBT	-129.3	-129.3	279.4	-79.0	-127.4	-125.6	-64.8	-77.9	-39.7	-37.0	-37.2	-14.9	-11.1
Income Tax Expense	0.8	0.8	4.2	0.0	-4.0	-2.9	1.3	-0.7	-0.8	-0.4	4.2	0.1	1.8
Net Income	-130.1	-130.1	275.2	-79.0	-123.4	-122.6	-66.2	-77.2	-38.9	-37.0	-37.2	-14.9	-11.1

Net Income	TTM	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Interest Income	6.8	7.0	7.4	7.6	6.9	7.7	7.4	4.4	4.2	4.3
Interest Expense	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0
Other Expense	6.6	7.1	7.4	7.7	6.9	7.8	7.5	4.4	4.3	4.2
IBT	-43.7	-39.3	-34.6	-11.7	133.7	-33.6	-31.3	210.7	27.3	-34.1
Income Tax Expense	0.7	0.0	0.2	0.0	2.0	-0.4	-0.7	3.3	-4.2	-0.8
Net Income	-44.4	-39.3	-34.8	-11.7	131.7	-33.2	-30.6	207.3	27.3	-34.1

Per Share Data	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
EPS	$0.00	$0.00	$0.00	$-1.39	$-2.52	$-2.65	$-1.92	$-2.98	$-1.74	$-2.09	$-5.72	$-2.52	$-1.88
EPS Diluted	$0.00	$0.00	$0.00	$-1.39	$-2.52	$-2.65	$-1.92	$-2.98	$-1.74	$-2.09	$-5.72	$-2.52	$-1.88
Shares Outstanding	63.6	63.6	61.6	56.8	49.0	46.3	34.4	25.9	22.4	17.7	6.5	5.9	5.9
Diluted Shares Outstanding	63.6	63.6	65.1	56.8	49.0	46.3	34.4	25.9	22.4	17.7	6.5	5.9	5.9

Per Share Data	TTM	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
EPS	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.45	$-0.58
EPS Diluted	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.44	$-0.58
Shares Outstanding	63.6	63.8	63.5	63.0	62.3	61.8	61.3	60.9	60.4	59.2
Diluted Shares Outstanding	63.6	63.8	63.5	63.0	66.4	61.8	61.3	63.6	61.8	59.2

Current Assets	TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Cash And Equivalents	355.6	97.2	186.7	125.7	123.7	117.4	33.0	82.2	106.0	21.1	4.1	9.3
Short Term Investments	208.4	321.7	154.9	111.6	203.2	188.5	100.0	46.6	38.0	56.5	7.9	0.0
Total Cash & ST Investments	564.0	418.9	341.6	237.4	326.9	307.8	133.0	128.9	155.5	87.7	11.9	9.3
Accounts Receivable	1.4	168.5	10.3	0.1	4.4	3.5	6.8	6.0	3.2	2.2	0.7	0.5
Inventory	0.0	0.0	0.0	-0.1	8.5	4.0	4.8	2.1	-8.7	-7.7	1.3	0.0
Other Current Assets	5.6	4.2	3.6	0.0	1.0	0.3	0.7	0.5	1.1	0.9	0.3	0.1
Total Current Assets	570.9	591.6	355.6	237.4	340.7	315.6	145.3	137.5	150.9	83.2	14.2	9.9

Current Assets	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Cash And Equivalents	113.7	168.5	139.7	97.2	131.1	355.6	172.6	186.7	230.5	235.4
Short Term Investments	462.4	401.9	434.7	321.7	337.6	208.4	150.1	154.9	90.2	78.0
Total Cash & ST Investments	576.1	570.5	574.4	418.9	468.7	564.0	322.6	341.6	322.7	313.4
Accounts Receivable	0.6	28.0	27.1	168.5	2.7	1.4	300.4	10.3	0.1	0.1
Inventory	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.1	-0.1
Other Current Assets	9.7	4.1	4.4	4.2	5.4	5.6	4.5	3.6	4.1	3.5
Total Current Assets	586.4	602.5	605.9	591.6	476.8	570.9	627.6	355.6	324.9	316.9

Long-Term Assets	TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Net Property, Plant & Equipment	12.0	12.6	2.1	4.6	6.7	6.4	7.7	0.9	0.9	0.6	0.6	0.4
Goodwill	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Intangible Assets	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Long-Term Investments	31.7	140.3	0.0	0.0	0.0	2.0	0.0	0.0	11.5	10.2	0.0	0.0
Other Long-Term Assets	0.0	0.2	0.2	5.9	0.2	0.5	0.5	0.5	0.5	0.0	0.0	0.0
Total Long-Term Assets	43.7	153.1	2.4	10.6	7.0	8.9	9.6	2.0	12.8	10.7	0.6	0.4
Total Assets	614.6	744.7	358.0	247.9	347.7	324.5	154.9	139.5	163.7	94.0	14.8	10.3

Long-Term Assets	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Net Property, Plant & Equipment	12.3	12.7	12.5	12.6	12.3	12.0	1.5	2.1	2.9	3.3
Goodwill	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Intangible Assets	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Long-Term Investments	102.7	102.5	123.5	140.3	114.6	31.4	0.0	0.2	2.0	0.2
Other Long-Term Assets	0.3	0.3	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.0
Total Long-Term Assets	115.3	115.5	136.3	153.1	127.1	43.7	1.7	2.4	5.1	3.5
Total Assets	701.7	718.0	742.1	744.7	603.9	614.6	629.3	358.0	330.0	320.5

Current Liabilities	TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Accounts Payable	3.6	1.6	0.8	3.6	1.6	3.1	2.8	5.7	1.3	1.2	1.2	0.3
Short-Term Debt	2.7	0.5	2.3	2.5	2.2	1.5	1.3	1.1	0.0	0.0	0.0	0.0
Other Current Liabilities	15.2	23.7	18.2	25.0	38.6	21.2	-10.2	11.2	9.5	5.3	1.9	1.0
Current Liabilities	41.6	47.4	21.3	31.2	44.0	40.2	35.4	26.2	42.6	6.4	3.1	1.4

Current Liabilities	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Accounts Payable	5.6	3.2	2.9	1.6	3.0	3.6	3.5	0.8	1.3	4.6
Short-Term Debt	2.2	2.2	1.6	0.5	0.0	0.0	0.5	2.3	3.6	4.9
Other Current Liabilities	37.1	15.4	11.8	23.7	20.7	15.2	16.5	18.2	23.0	16.9
Current Liabilities	44.9	35.5	35.1	47.4	44.6	41.6	39.9	21.3	27.9	26.4

Long-Term Liabilities	TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Long-Term Debt	11.0	10.4	0.0	1.1	3.7	4.5	15.8	0.0	0.0	0.0	0.0	0.0
Capital Leases	11.0	10.9	1.1	3.7	5.9	6.0	7.2	0.0	0.0	0.0	0.0	0.0
Def. Tax Liability	-20.8	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Total Liabilities	73.3	69.4	21.3	784.7	47.7	44.9	75.0	27.0	43.1	6.4	5.2	2.4

Long-Term Liabilities	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Long-Term Debt	8.5	9.1	9.8	10.4	10.9	11.0	0.0	0.0	0.0	0.0
Capital Leases	10.7	11.3	11.4	10.9	10.9	11.0	0.5	1.1	1.8	2.4
Def. Tax Liability	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0
Total Liabilities	56.3	50.0	53.1	69.4	71.9	73.3	68.8	21.3	27.9	26.4

Total Common Equity	TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Common Stock	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-247.2	-0.9	-0.7
Retained Earnings	-439.0	-340.5	-615.7	-536.8	-409.4	-283.8	-217.7	-140.5	-101.6	-64.6	-27.4	-12.6
Comprehensive Income	-0.2	-0.1	-0.1	-0.4	-0.3	0.0	-0.2	-0.2	0.0	-0.2	-0.1	-0.1
Total Common Equity	541.3	675.3	336.7	-536.8	-409.4	-283.8	-217.7	-140.5	-101.6	-64.6	9.6	8.0

Total Common Equity	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Common Stock	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Retained Earnings	-426.3	-386.9	-352.2	-340.5	-472.2	-439.0	-408.4	-615.7	-643.0	-608.9
Comprehensive Income	0.5	0.0	0.1	-0.1	1.3	-0.2	-0.2	-0.1	-0.2	-0.2
Total Common Equity	645.4	668.0	689.1	675.3	531.9	541.3	560.4	336.7	-643.0	294.1

Other		TTM	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Total Debt		11.0	10.9	1.1	3.7	5.9	6.0	17.0	0.0	0.0	0.0	0.0	0.0
Book Value		541.3	675.3	336.7	-536.8	300.0	279.6	80.0	112.5	120.6	87.6	9.6	8.0

Other		3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023	2-2023
Total Debt		0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Book Value		645.4	668.0	689.1	675.3	531.9	541.3	560.4	336.7	-643.0	294.1

Cash Flow From Operating Activities	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Net Income	170.0	0.0	275.2	-79.0	-127.4	-125.6	-66.2	-77.2	-38.9	-37.0	-37.2	-14.9	-11.1
Depreciation & Amortization	3.4	0.0	2.9	3.3	3.4	2.8	2.6	2.5	0.5	0.4	0.3	0.2	0.3
Stock-Based Compensation	31.7	46.0	37.6	29.3	24.2	16.4	7.9	8.4	6.9	4.2	2.1	0.1	0.0
Change Working Capital	32.2	146.2	-122.6	-19.5	-7.8	-3.3	-19.0	26.1	-18.0	35.6	-0.1	0.1	1.3
Change In Accounts Receivable	0.0	164.9	-155.0	0.0	0.0	0.0	0.0	0.0	-2.8	-1.8	0.0	0.0	0.0
Change In Accounts Payable	-1.2	3.7	0.8	-2.9	2.0	-1.4	0.3	-3.0	4.4	0.1	-0.1	0.9	0.2
Change In Inventories	10.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.9	5.5	0.0	0.0	0.0
Other Non-cash Items	10.3	-134.5	-8.9	-4.4	-0.5	1.8	0.8	-0.6	0.2	0.6	4.7	0.1	1.8
Cash from Operations	231.5	0.0	0.0	-70.2	-108.1	-107.9	-72.5	-41.5	-49.9	3.9	-30.0	-14.4	-7.7

Cash Flow From Operating Activities	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Net Income	85.8	-39.3	-34.8	-11.7	131.7	-33.2	-30.6	207.3	27.3	-34.1
Depreciation & Amortization	-0.9	0.4	0.3	0.2	0.5	0.6	0.9	0.8	0.8	0.8
Stock-Based Compensation	10.7	0.0	10.9	13.8	9.1	0.0	0.0	0.0	6.6	6.8
Change Working Capital	-2.7	28.1	-3.9	124.7	-167.7	-2.6	291.1	-243.3	-16.5	0.9
Change In Accounts Receivable	0.5	-0.6	0.5	165.0	-165.0	0.0	300.0	-290.0	-10.0	0.0
Change In Accounts Payable	-0.3	2.4	0.4	1.2	-1.4	-0.4	-0.2	2.8	-0.6	-3.2
Change In Inventories	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.0	0.0
Other Non-cash Items	-129.9	9.0	-1.3	-1.7	-2.8	7.3	7.3	7.7	-1.3	5.8
Cash from Operations	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	17.0	-26.6

Cash Flow From Investing Activities	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Capital Expenditure	-0.7	-1.6	-1.4	-0.6	-0.8	-1.1	-0.5	-1.0	-0.5	-0.7	-0.4	-0.4	-0.3
Acquisitions	74.4	0.0	0.0	0.0	-91.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Investments	-397.6	-546.6	-621.7	-191.0	-214.9	-286.6	-280.0	-166.9	-71.1	-39.5	-73.2	-7.9	0.0
Sales of Investment	241.3	498.8	323.6	152.4	307.1	271.8	189.5	114.2	73.8	56.0	14.2	0.0	0.0
Other Investing Activities	-156.2	0.0	0.0	0.0	91.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cash from Investing	-156.9	0.0	0.0	-39.3	91.5	-15.9	-91.0	-53.7	2.2	15.8	-59.3	-8.3	-0.3

Cash Flow From Investing Activities	4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Capital Expenditure	1.4	-0.1	-0.8	-0.5	-0.3	-0.8	0.0	-0.2	0.0	-0.4
Acquisitions	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	61.3	13.2
Investments	442.3	-161.1	-67.2	-214.0	-114.4	-266.7	-175.0	-65.7	-98.0	-59.0
Sales of Investment	-345.6	102.7	122.8	120.2	106.0	58.7	86.9	72.0	36.7	45.8
Other Investing Activities	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-61.3	-13.2
Cash from Investing	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-61.3	-13.6

Cash Flow From Financing Activities	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Debt Repaid	0.0	0.0	0.0	0.0	0.0	0.0	-10.5	0.0	0.0	0.0	0.0	0.0	0.0
Debt Issued	8.5	10.9	9.7	-2.5	-2.2	-0.1	-0.5	17.0	0.0	0.0	0.0	0.0	0.0
Issuance of Common Stock	46.2	0.0	0.0	132.1	14.6	123.8	255.4	34.5	23.2	64.5	83.6	0.0	0.0
Repurchase of Common Stock	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Dividends Paid	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Other Financing Activities	37.8	0.0	0.0	38.4	4.3	6.1	2.8	11.5	0.9	1.0	22.7	17.4	9.0
Cash from Financing	45.6	0.0	0.0	170.5	18.8	129.9	247.6	46.0	24.1	65.6	106.3	17.4	9.0

Cash Flow From Financing Activities	4-2025	3-2025	2-2025	1-2025	3-2024	2-2024	1-2024	4-2023	3-2023
Debt Repaid	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Debt Issued	10.7	-0.5	-0.1	0.5	-0.1	10.5	-0.7	-0.7	-0.6
Issuance of Common Stock	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.1
Repurchase of Common Stock	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Dividends Paid	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Other Financing Activities	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	35.3
Cash from Financing	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	35.3

Cash position		TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Net Change in Cash		120.3	31.1	-89.5	61.0	2.1	6.1	84.4	-49.2	-23.8	85.4	17.0	-5.3	0.9
Closing Cash Balance		355.6	128.4	97.5	187.0	126.0	123.9	117.8	33.5	82.7	106.5	21.1	4.1	9.3

Cash position		4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Net Change in Cash		14.7	-54.8	29.0	42.4	-33.9	-224.5	183.1	-14.2	-43.8	-4.9
Closing Cash Balance		128.4	113.7	168.8	139.7	97.5	131.1	355.6	172.6	187.0	230.8

Free Cash Flow		TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Free Cash Flow		230.8	56.1	182.8	-70.8	-108.9	-109.0	-73.0	-42.5	-50.4	3.2	-30.4	-14.8	-8.0
Real Free Cash Flow		199.2	10.1	145.2	-100.1	-133.1	-125.4	-80.9	-50.8	-57.4	-1.0	-32.5	-14.9	-8.1

Free Cash Flow		4-2025	3-2025	2-2025	1-2025	4-2024	3-2024	2-2024	1-2024	4-2023	3-2023
Free Cash Flow		-35.5	-2.0	-29.6	124.8	-29.5	-28.6	268.6	-27.7	16.9	-27.0
Real Free Cash Flow		-46.2	-2.0	-40.5	111.0	-38.6	-28.6	268.6	-27.7	10.3	-33.8